The Great Patriotic War is a period when the whole country defended its independence in the face of fascism. All the rear regions, including the Mari Autonomous Soviet Socialist Republic, made their own contribution to the defeat of the enemy. The purpose of this article is to analyze the contribution of women of the city of Volzhsk and the Volzhsk district of the Mari ASSR to the victory during the Great Patriotic War of 1941‒1945 based on the materials of the regional newspaper “Volzhskaya Pravda”. Their role in the development of agriculture, industry, education and their wide participation in the patriotic movement to help the front are considered. The main research methods were both general scientific (comparison, analysis, description) and special-historical (historical-genetic, historical-comparative) methods. The work is based on a wide range of scientific literature and a unique historical source. With the beginning of the Great Patriotic War, the bulk of the able-bodied male population was mobilized to the front, and therefore there was an acute shortage of qualified workers. In the Volzhsk district, as well as throughout the republic, men who went to the front in almost all spheres of public life were replaced by women. In agriculture, the women of the region worked in the fields, entered into socialist competition, fought for the preservation of livestock, and mastered new professions. At existing industrial enterprises, women workers fulfilled and exceeded the established plans, joined the Stakhanov movement, continued to work at the machines instead of their husbands, fathers and brothers. A wide manifestation of patriotism was the involvement of the entire population, including the women of the region, in the movement to raise funds for the construction of military equipment, warm clothes and gifts for the soldiers of the Red Army. In the field of education in the city of Volzhsk and in the Volzhsk district, pedagogical workers fought for the progress of students, provided all possible assistance to collective farms and involved school-age children in work in the fields. During the Great Patriotic War, the female population of the Volzhsk district made a significant contribution to the development of the republic, thereby bringing the Victory closer.